Atopic Dermatitis and the Immune System

Neurodermatitis is a chronic inflammatory skin condition that is associated with a malfunction of the immune system. While the immune system in affected children reacts hypersensitively to certain stimuli, this does not mean they are excluded from vaccinations. On the contrary: vaccinations are also important for children with eczema, as they provide protection against potentially dangerous infectious diseases.

Are vaccinations safe for atopic dermatitis?

Yes, vaccinations are safe for children with eczema. The standard vaccinations, as listed in the vaccination recommendations of the Standing Committee on Vaccination (STIKO), can generally be carried out without concern. Studies show that children with neurodermatitis do not have significantly higher risks of severe side effects from vaccinations compared to healthy children.

However, parents should inform the treating physician about their child's neurodermatitis so that possible skin reactions can be better assessed.

Skin reactions after vaccinations

Children with eczema may occasionally show stronger skin reactions after vaccinations. These may include:

• Ring-shaped redness and swelling at the injection site

• Increased itching

• Temporary worsening of eczema

These reactions are usually mild and temporary. They typically resolve within a few days and do not pose an obstacle to future vaccinations.

When should the vaccination be postponed?

In some cases, it may be advisable to postpone the vaccination appointment, for example:

• During an acute neurodermatitis flare-up, as the immune system is already stressed.

• If the child has a cold or fever.

However, once the flare-up has subsided, the vaccination can be easily caught up.

Can vaccination still occur despite corticosteroid cream treatment?

A therapy with corticosteroids normally does not pose an obstacle to recommended vaccinations. There is no scientific evidence that vaccinations are significantly impaired by the treatment.

Conclusion

• The STIKO recommends vaccinations for toddlers and adolescents.

• If possible, vaccination should be avoided during a disease flare-up.

• Allergic reactions related to vaccinations are extremely rare and occur no more frequently in those affected by neurodermatitis than in those with healthy skin.

• If the skin condition worsens, it is advisable to consult a pediatrician or dermatologist.

Sources

1. AWMF (2024). S3 Guideline Atopic Dermatitis.

2. please touch - Hand in Hand against Neurodermatitis (2024). Vaccination in Neurodermatitis.